Cellular uptake of modified aminoglycosides
نویسندگان
چکیده
منابع مشابه
Cellular uptake of aminoglycosides, guanidinoglycosides, and poly-arginine.
Aminoglycosides (including neomycin B and tobramycin) exhibit poor uptake by eukaryotic cell lines. When the amines of these natural products are converted into guanidine groups, their cellular uptake is dramatically enhanced. We have synthesized BODIPY-containing aminoglycosides and guanidinoglycosides to evaluate their cellular uptake properties. Fluorescence activated cell sorting (FACS) and...
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چکیده ندارد.
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 2017
ISSN: 0021-8820,1881-1469
DOI: 10.1038/ja.2017.131